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Stem cell lineage survival as a noisy competition for niche access
Understanding to what extent stem cell potential is a cell-intrinsic property or an emergent behavior coming from global tissue dynamics and geometry is a key outstanding question of systems and stem cell biology. Here, we propose a theory of stem cell dynamics as a stochastic competition for access...
Autores principales: | Corominas-Murtra, Bernat, Scheele, Colinda L. G. J., Kishi, Kasumi, Ellenbroek, Saskia I. J., Simons, Benjamin D., van Rheenen, Jacco, Hannezo, Edouard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382312/ https://www.ncbi.nlm.nih.gov/pubmed/32611816 http://dx.doi.org/10.1073/pnas.1921205117 |
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