Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci

Currently, there is no comprehensive framework to evaluate the evolutionary forces acting on genomic regions associated with human complex traits and contextualize the relationship between evolution and molecular function. Here, we develop an approach to test for signatures of diverse evolutionary f...

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Detalles Bibliográficos
Autores principales: LaBella, Abigail L., Abraham, Abin, Pichkar, Yakov, Fong, Sarah L., Zhang, Ge, Muglia, Louis J., Abbot, Patrick, Rokas, Antonis, Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382462/
https://www.ncbi.nlm.nih.gov/pubmed/32709900
http://dx.doi.org/10.1038/s41467-020-17258-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382462/
https://www.ncbi.nlm.nih.gov/pubmed/32709900
http://dx.doi.org/10.1038/s41467-020-17258-6

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