Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca(V)3 T-type channels alter the passage and block of monovalent and divalent ions

Invertebrate LCa(V)3 shares the quintessential features of vertebrate Ca(V)3 T-type channels, with a low threshold of channel activation, rapid activation and inactivation kinetics and slow deactivation kinetics compared to other known Ca(2+) channels, the Ca(V)1 and Ca(V)2 channels. Unlike the vert...

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Detalles Bibliográficos
Autores principales: Guan, Wendy, Stephens, Robert F., Mourad, Omar, Mehta, Amrit, Fux, Julia, Spafford, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382465/
https://www.ncbi.nlm.nih.gov/pubmed/32710088
http://dx.doi.org/10.1038/s41598-020-69197-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382465/
https://www.ncbi.nlm.nih.gov/pubmed/32710088
http://dx.doi.org/10.1038/s41598-020-69197-3

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