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Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca(V)3 T-type channels alter the passage and block of monovalent and divalent ions
Invertebrate LCa(V)3 shares the quintessential features of vertebrate Ca(V)3 T-type channels, with a low threshold of channel activation, rapid activation and inactivation kinetics and slow deactivation kinetics compared to other known Ca(2+) channels, the Ca(V)1 and Ca(V)2 channels. Unlike the vert...
Autores principales: | Guan, Wendy, Stephens, Robert F., Mourad, Omar, Mehta, Amrit, Fux, Julia, Spafford, J. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382465/ https://www.ncbi.nlm.nih.gov/pubmed/32710088 http://dx.doi.org/10.1038/s41598-020-69197-3 |
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