A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

The increase of antimicrobial resistance (AMR), and lack of new classes of licensed antimicrobials, have made alternative treatment options for AMR pathogens increasingly attractive. Recent studies have demonstrated anti-bacterial efficacy of a humanised monoclonal antibody (mAb) targeting the O25b...

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Detalles Bibliográficos
Autores principales: Maes, Mailis, Dyson, Zoe A., Smith, Sarah E., Goulding, David A., Ludden, Catherine, Baker, Stephen, Kellam, Paul, Reece, Stephen T., Dougan, Gordon, Bartholdson Scott, Josefin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382476/
https://www.ncbi.nlm.nih.gov/pubmed/32709982
http://dx.doi.org/10.1038/s41598-020-69300-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382476/
https://www.ncbi.nlm.nih.gov/pubmed/32709982
http://dx.doi.org/10.1038/s41598-020-69300-8

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