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Immune checkpoint inhibitor induces cardiac injury through polarizing macrophages via modulating microRNA-34a/Kruppel-like factor 4 signaling

Cancer immunotherapy has become a well-established treatment option for some cancers; however, its use is hampered by its cardiovascular adverse effects. Immune checkpoint inhibitors (ICIs)-related cardiac toxicity took place in kinds of different forms, such as myocarditis, acute coronary syndrome,...

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Detalles Bibliográficos
Autores principales: Xia, Wenzheng, Zou, Changlin, Chen, Hanbin, Xie, Congying, Hou, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382486/
https://www.ncbi.nlm.nih.gov/pubmed/32709878
http://dx.doi.org/10.1038/s41419-020-02778-2