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Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice

Hydrocephalus is a brain disorder triggered by cerebrospinal fluid accumulation in brain cavities. Even though cerebrospinal fluid flow is known to be driven by the orchestrated beating of the bundled motile cilia of ependymal cells, little is known about the mechanism of ciliary motility. RSPH9 is...

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Detalles Bibliográficos
Autores principales: Zou, Wenzheng, Lv, Yuqing, Liu, Zux iang, Xia, Pengyan, Li, Hong, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382491/
https://www.ncbi.nlm.nih.gov/pubmed/32709945
http://dx.doi.org/10.1038/s41598-020-69447-4