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The cholinesterase inhibitor donepezil has antidepressant-like properties in the mouse forced swim test

Finding new antidepressant agents is of high clinical priority given that many cases of major depressive disorder (MDD) do not respond to conventional monoaminergic antidepressants such as the selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and monoamine oxidase inhibitor...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Paul J., Hale, Pho J., Ghimire, Anjesh, Watson, Brendon O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382650/
https://www.ncbi.nlm.nih.gov/pubmed/32712627
http://dx.doi.org/10.1038/s41398-020-00928-w