3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species

There is accumulating evidence showing that apoptosis induced by endoplasmic reticulum (ER) stress plays a key role in pancreatic β cell dysfunction and insulin resistance. 3β-Hydroxysteroid-Δ24 Reductase (DHCR24) is a multifunctional enzyme located in the endoplasmic reticulum (ER), which has been...

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Detalles Bibliográficos
Autores principales: Li, Yang, Wang, Xude, Yang, Baoyu, Wang, Haozhen, Ma, Zhenzhong, Lu, Ziyin, Lu, Xiuli, Gao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382746/
https://www.ncbi.nlm.nih.gov/pubmed/32724824
http://dx.doi.org/10.1155/2020/3426902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382746/
https://www.ncbi.nlm.nih.gov/pubmed/32724824
http://dx.doi.org/10.1155/2020/3426902

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