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Loratadine Alleviates Advanced Glycation End Product-Induced Activation of NLRP3 Inflammasome in Human Chondrocytes

BACKGROUND: Chondrocytes in joint tissue are responsible for the synthesis and degradation of the cartilage matrix. Chondrocytes have been closely linked to the pathogenesis of osteoarthritis and cartilage damage. Targeted drug intervention directed at chondrocyte function is a promising strategy fo...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Zhang, Shanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382759/
https://www.ncbi.nlm.nih.gov/pubmed/32801633
http://dx.doi.org/10.2147/DDDT.S243512