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Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast

Governance of protein phosphorylation by kinases and phosphatases constitutes an essential regulatory network in eukaryotic cells. Network dysregulation leads to severe consequences and is often a key factor in disease pathogenesis. Previous studies revealed multiple roles for protein phosphorylatio...

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Detalles Bibliográficos
Autores principales: Li, Jiaming, Paulo, Joao A., Nusinow, David P., Huttlin, Edward L., Gygi, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382779/
https://www.ncbi.nlm.nih.gov/pubmed/31722220
http://dx.doi.org/10.1016/j.celrep.2019.10.034