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Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast
Governance of protein phosphorylation by kinases and phosphatases constitutes an essential regulatory network in eukaryotic cells. Network dysregulation leads to severe consequences and is often a key factor in disease pathogenesis. Previous studies revealed multiple roles for protein phosphorylatio...
Autores principales: | Li, Jiaming, Paulo, Joao A., Nusinow, David P., Huttlin, Edward L., Gygi, Steven P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382779/ https://www.ncbi.nlm.nih.gov/pubmed/31722220 http://dx.doi.org/10.1016/j.celrep.2019.10.034 |
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