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Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results
BACKGROUND: Early treatment with tranexamic acid may reduce deaths after traumatic brain injury (TBI). In mild and moderate TBI, there is a time to treatment interaction, with early treatment being most beneficial. Time to treatment was recorded by clinicians and is subject to error. Using monitorin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382791/ https://www.ncbi.nlm.nih.gov/pubmed/32711551 http://dx.doi.org/10.1186/s13063-020-04623-5 |