Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

BACKGROUND: Adaptive Laboratory Evolution (ALE) has emerged as an experimental approach to discover mutations that confer phenotypic functions of interest. However, the task of finding and understanding all beneficial mutations of an ALE experiment remains an open challenge for the field. To provide...

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Detalles Bibliográficos
Autores principales: Phaneuf, Patrick V., Yurkovich, James T., Heckmann, David, Wu, Muyao, Sandberg, Troy E., King, Zachary A., Tan, Justin, Palsson, Bernhard O., Feist, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382830/
https://www.ncbi.nlm.nih.gov/pubmed/32711472
http://dx.doi.org/10.1186/s12864-020-06920-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382830/
https://www.ncbi.nlm.nih.gov/pubmed/32711472
http://dx.doi.org/10.1186/s12864-020-06920-4

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