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Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity
BACKGROUND: Adaptive Laboratory Evolution (ALE) has emerged as an experimental approach to discover mutations that confer phenotypic functions of interest. However, the task of finding and understanding all beneficial mutations of an ALE experiment remains an open challenge for the field. To provide...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382830/ https://www.ncbi.nlm.nih.gov/pubmed/32711472 http://dx.doi.org/10.1186/s12864-020-06920-4 |