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MicroRNA-503-3p affects osteogenic differentiation of human adipose-derived stem cells by regulation of Wnt2 and Wnt7b under cyclic strain

BACKGROUND: MicroRNAs (miRNAs) play a role in regulating osteogenic differentiation (OD) of mesenchymal stem cells by inhibiting mRNAs translation under cyclic strain. miR-503-3p was downregulated in OD of human adipose-derived stem cells (hASCs) in vivo under cyclic strain in our previous study, wh...

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Detalles Bibliográficos
Autores principales: Luo, Yadong, Ding, Xu, Ji, Huan, Li, Meng, Song, Haiyang, Li, Sheng, Wang, Chenxing, Wu, Heming, Du, Hongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382842/
https://www.ncbi.nlm.nih.gov/pubmed/32711579
http://dx.doi.org/10.1186/s13287-020-01842-0