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MAPK4 deletion enhances radiation effects and triggers synergistic lethality with simultaneous PARP1 inhibition in cervical cancer

BACKGROUND: Cervical cancer is one of the most common cancers among females worldwide and advanced patients have extremely poor prognosis. However, adverse reactions and accumulating resistance to radiation therapy require further investigation. METHODS: The expression levels of mitogen-activated pr...

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Detalles Bibliográficos
Autores principales: Tian, Shuzhen, Lou, Lili, Tian, Mengyuan, Lu, Guangping, Tian, Jianghua, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382858/
https://www.ncbi.nlm.nih.gov/pubmed/32711558
http://dx.doi.org/10.1186/s13046-020-01644-5