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MAPK4 deletion enhances radiation effects and triggers synergistic lethality with simultaneous PARP1 inhibition in cervical cancer
BACKGROUND: Cervical cancer is one of the most common cancers among females worldwide and advanced patients have extremely poor prognosis. However, adverse reactions and accumulating resistance to radiation therapy require further investigation. METHODS: The expression levels of mitogen-activated pr...
Autores principales: | Tian, Shuzhen, Lou, Lili, Tian, Mengyuan, Lu, Guangping, Tian, Jianghua, Chen, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382858/ https://www.ncbi.nlm.nih.gov/pubmed/32711558 http://dx.doi.org/10.1186/s13046-020-01644-5 |
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