Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes

BACKGROUND: Spinal cord injury (SCI) is a catastrophic injury that can cause irreversible motor dysfunction with high disability. Exosomes participate in the transport of miRNAs and play an essential role in intercellular communication via transfer of genetic material. However, the miRNAs in exosome...

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Detalles Bibliográficos
Autores principales: Jiang, Dongdong, Gong, Fangyi, Ge, Xuhui, Lv, Chengtang, Huang, Chenyu, Feng, Shuang, Zhou, Zheng, Rong, Yuluo, Wang, Jiaxing, Ji, Chengyue, Chen, Jian, Zhao, Wene, Fan, Jin, Liu, Wei, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382861/
https://www.ncbi.nlm.nih.gov/pubmed/32711535
http://dx.doi.org/10.1186/s12951-020-00665-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382861/
https://www.ncbi.nlm.nih.gov/pubmed/32711535
http://dx.doi.org/10.1186/s12951-020-00665-8

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