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The evolution of Tamiflu synthesis, 20 years on: Advent of enabling technologies the last piece of the puzzle?

Influenza is a serious respiratory disease responsible for significant morbidity and mortality due to both annual epidemics and pandemics; its treatment involves the use of neuraminidase inhibitors. (−)-Oseltamivir phosphate (Tamiflu) approved in 1999, is one of the most potent oral anti-influenza n...

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Detalles Bibliográficos
Autores principales: Sagandira, Cloudius R., Mathe, Francis M., Guyo, Upenyu, Watts, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382934/
https://www.ncbi.nlm.nih.gov/pubmed/32839628
http://dx.doi.org/10.1016/j.tet.2020.131440