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The evolution of Tamiflu synthesis, 20 years on: Advent of enabling technologies the last piece of the puzzle?
Influenza is a serious respiratory disease responsible for significant morbidity and mortality due to both annual epidemics and pandemics; its treatment involves the use of neuraminidase inhibitors. (−)-Oseltamivir phosphate (Tamiflu) approved in 1999, is one of the most potent oral anti-influenza n...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382934/ https://www.ncbi.nlm.nih.gov/pubmed/32839628 http://dx.doi.org/10.1016/j.tet.2020.131440 |