External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study

BACKGROUND: The Dutch Pediatric Formulary (DPF) increasingly bases its guidelines on model-based dosing simulations from pharmacokinetic studies. This resulted in nationwide dose changes for vancomycin, gentamicin, and tobramycin in 2015. OBJECTIVE: We aimed to evaluate target attainment of these al...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartman, Stan J. F., Orriëns, Lynn B., Zwaag, Samanta M., Poel, Tim, de Hoop, Marika, de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383037/
https://www.ncbi.nlm.nih.gov/pubmed/32507958
http://dx.doi.org/10.1007/s40272-020-00400-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383037/
https://www.ncbi.nlm.nih.gov/pubmed/32507958
http://dx.doi.org/10.1007/s40272-020-00400-8

Ejemplares similares