Polyphyllin I Promoted Melanoma Cells Autophagy and Apoptosis via PI3K/Akt/mTOR Signaling Pathway

To investigate whether Polyphyllin I (PPI) might induce the autophagy and apoptosis of melanoma cells by regulating PI3K/Akt/mTOR signal pathway. Melanoma A375 cells were incubated with different concentrations of Polyphyllin I (0, 1.5, 3.0, and 6.0 mg/L) and PI3K/Akt/mTOR signaling pathway activato...

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Detalles Bibliográficos
Autores principales: Long, Jianwen, Pi, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383336/
https://www.ncbi.nlm.nih.gov/pubmed/32733943
http://dx.doi.org/10.1155/2020/5149417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383336/
https://www.ncbi.nlm.nih.gov/pubmed/32733943
http://dx.doi.org/10.1155/2020/5149417

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