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Development of near‐infrared firefly luciferin analogue reacted with wild‐type and mutant luciferases

Interestingly, only the D‐form of firefly luciferin produces light by luciferin–luciferase (L–L) reaction. Certain firefly luciferin analogues with modified structures maintain bioluminescence (BL) activity; however, all L‐form luciferin analogues show no BL activity. To this date, our group has dev...

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Detalles Bibliográficos
Autores principales: Kitada, Nobuo, Saito, Ryohei, Obata, Rika, Iwano, Satoshi, Karube, Kazuma, Miyawaki, Atsushi, Hirano, Takashi, Maki, Shojiro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383472/
https://www.ncbi.nlm.nih.gov/pubmed/32367573
http://dx.doi.org/10.1002/chir.23236