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In the presence of Trypanosoma cruzi antigens, activated peripheral T lymphocytes retained in the liver induce a proinflammatory phenotypic and functional shift in intrahepatic T lymphocyte

In secondary lymphoid organs, pathogen‐derived and endogenous danger molecules are recognized by pattern recognition receptors, leading to adaptive proinflammatory immune responses. This conceptual rule does not apply directly to the liver, as hepatic immune cells tolerate gut‐derived bacterial mole...

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Detalles Bibliográficos
Autores principales: Meuser‐Batista, Marcelo, Vacani‐Martins, Natalia, Cascabulho, Cynthia Machado, Beghini, Daniela Gois, Henriques‐Pons, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383480/
https://www.ncbi.nlm.nih.gov/pubmed/32202341
http://dx.doi.org/10.1002/JLB.3A0220-399RR