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Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines

Miniaturization and acceleration of synthetic chemistry is an emerging area in pharmaceutical, agrochemical, and materials research and development. Herein, we describe the synthesis of iminopyrrolidine‐2‐carboxylic acid derivatives using chiral glutamine, oxo components, and isocyanide building blo...

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Detalles Bibliográficos
Autores principales: Osipyan, Angelina, Shaabani, Shabnam, Warmerdam, Robert, Shishkina, Svitlana V., Boltz, Harry, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383484/
https://www.ncbi.nlm.nih.gov/pubmed/32048418
http://dx.doi.org/10.1002/anie.202000887