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Reagents for Selective Fluoromethylation: A Challenge in Organofluorine Chemistry
The introduction of a monofluoromethyl moiety has undoubtedly become a very important area of research in recent years. Owing to the beneficial properties of organofluorine compounds, such as their metabolic stability, the incorporation of the CH(2)F group as a bioisosteric substitute for various fu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383490/ https://www.ncbi.nlm.nih.gov/pubmed/32022357 http://dx.doi.org/10.1002/anie.201913175 |