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Reagents for Selective Fluoromethylation: A Challenge in Organofluorine Chemistry

The introduction of a monofluoromethyl moiety has undoubtedly become a very important area of research in recent years. Owing to the beneficial properties of organofluorine compounds, such as their metabolic stability, the incorporation of the CH(2)F group as a bioisosteric substitute for various fu...

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Detalles Bibliográficos
Autores principales: Reichel, Marco, Karaghiosoff, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383490/
https://www.ncbi.nlm.nih.gov/pubmed/32022357
http://dx.doi.org/10.1002/anie.201913175