Designed Asymmetric Protein Assembly on a Symmetric Scaffold

Cellular signaling is regulated by the assembly of proteins into higher‐order complexes. Bottom‐up creation of synthetic protein assemblies, especially asymmetric complexes, is highly challenging. Presented here is the design and implementation of asymmetric assembly of a ternary protein complex fac...

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Detalles Bibliográficos
Autores principales: Lemmens, Lenne J. M., Roodhuizen, Job A. L., de Greef, Tom F. A., Markvoort, Albert J., Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383506/
https://www.ncbi.nlm.nih.gov/pubmed/32333708
http://dx.doi.org/10.1002/anie.202003626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383506/
https://www.ncbi.nlm.nih.gov/pubmed/32333708
http://dx.doi.org/10.1002/anie.202003626

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