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Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin

Psilocybin, the principal indole alkaloid of Psilocybe mushrooms, is currently undergoing clinical trials as a medication against treatment‐resistant depression and major depressive disorder. The psilocybin supply for pharmaceutical purposes is met by synthetic chemistry. We replaced the problematic...

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Detalles Bibliográficos
Autores principales: Fricke, Janis, Kargbo, Robert, Regestein, Lars, Lenz, Claudius, Peschel, Gundela, Rosenbaum, Miriam A., Sherwood, Alexander, Hoffmeister, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383583/
https://www.ncbi.nlm.nih.gov/pubmed/32101345
http://dx.doi.org/10.1002/chem.202000134