PARP inhibition and immune modulation: scientific rationale and perspectives for the treatment of gynecologic cancers

Poly[adenosine diphosphate (ADP) ribose]polymerase (PARP) has multifaceted roles in the maintenance of genomic integrity, deoxyribonucleic acid (DNA) repair and replication, and the maintenance of immune-system homeostasis. PARP inhibitors are an attractive oncologic therapy, causing direct cancer c...

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Detalles Bibliográficos
Autores principales: Lee, Elizabeth K., Konstantinopoulos, Panagiotis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Immunotherapy in Gynecological Cancers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383615/
https://www.ncbi.nlm.nih.gov/pubmed/32782491
http://dx.doi.org/10.1177/1758835920944116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383615/
https://www.ncbi.nlm.nih.gov/pubmed/32782491
http://dx.doi.org/10.1177/1758835920944116

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