Sequence‐Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases

Certain hydrolases preferentially catalyze acyl transfer over hydrolysis in an aqueous environment. However, the molecular and structural reasons for this phenomenon are still unclear. Herein, we provide evidence that acyltransferase activity in esterases highly correlates with the hydrophobicity of...

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Detalles Bibliográficos
Autores principales: Müller, Henrik, Becker, Ann‐Kristin, Palm, Gottfried J., Berndt, Leona, Badenhorst, Christoffel P. S., Godehard, Simon P., Reisky, Lukas, Lammers, Michael, Bornscheuer, Uwe T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383625/
https://www.ncbi.nlm.nih.gov/pubmed/32243661
http://dx.doi.org/10.1002/anie.202003635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383625/
https://www.ncbi.nlm.nih.gov/pubmed/32243661
http://dx.doi.org/10.1002/anie.202003635

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