Performance of the pattern‐based interpretation of p53 immunohistochemistry as a surrogate for TP53 mutations in vulvar squamous cell carcinoma

AIMS: The most commonly mutated gene in vulvar squamous cell carcinoma (VSCC) is TP53 and its prognostic value, particularly in HPV‐independent VSCC, is uncertain. In other tumours, p53 immunohistochemistry (IHC) is an excellent surrogate marker for TP53 mutations. In order to study this in VSCC, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Kortekaas, Kim E, Solleveld‐Westerink, Nienke, Tessier‐Cloutier, Basile, Rutten, Tessa A, Poelgeest, Mariëtte I E, Gilks, C Blake, Hoang, Lien N, Bosse, Tjalling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383647/
https://www.ncbi.nlm.nih.gov/pubmed/32236967
http://dx.doi.org/10.1111/his.14109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383647/
https://www.ncbi.nlm.nih.gov/pubmed/32236967
http://dx.doi.org/10.1111/his.14109

Ejemplares similares