Performance of the pattern‐based interpretation of p53 immunohistochemistry as a surrogate for TP53 mutations in vulvar squamous cell carcinoma

AIMS: The most commonly mutated gene in vulvar squamous cell carcinoma (VSCC) is TP53 and its prognostic value, particularly in HPV‐independent VSCC, is uncertain. In other tumours, p53 immunohistochemistry (IHC) is an excellent surrogate marker for TP53 mutations. In order to study this in VSCC, we...

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Detalles Bibliográficos
Autores principales: Kortekaas, Kim E, Solleveld‐Westerink, Nienke, Tessier‐Cloutier, Basile, Rutten, Tessa A, Poelgeest, Mariëtte I E, Gilks, C Blake, Hoang, Lien N, Bosse, Tjalling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
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Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383647/
https://www.ncbi.nlm.nih.gov/pubmed/32236967
http://dx.doi.org/10.1111/his.14109

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