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Cell function profiling to assess clone stability

In cell line development the identification of stable Chinese hamster ovary cells for production is a critical but onerous task. The stability trial focus upon high‐level attributes can mask profound underlying cellular changes, leading to unstable clones mistakenly being chosen for production. The...

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Detalles Bibliográficos
Autores principales: Dobson, Paul D., Coss, Karen P., Doherty, Carolanne, Clifford, Jerry, Thompson, Ben, James, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383652/
https://www.ncbi.nlm.nih.gov/pubmed/32181887
http://dx.doi.org/10.1002/bit.27336