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Sex‐specific alterations in whole body energetics and voluntary activity in heterozygous R163C malignant hyperthermia‐susceptible mice

Malignant hyperthermia (MH) is characterized by induction of skeletal muscle hyperthermia in response to a dysregulated increase in myoplasmic calcium. Although altered energetics play a central role in MH, MH‐susceptible humans and mouse models are often described as having no phenotype until expos...

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Detalles Bibliográficos
Autores principales: Rutkowsky, Jennifer M., Knotts, Trina A., Allen, Paul D., Pessah, Isaac N., Ramsey, Jon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383697/
https://www.ncbi.nlm.nih.gov/pubmed/32367593
http://dx.doi.org/10.1096/fj.202000403