Design and Characterization of a New pVII Combinatorial Phage Display Peptide Library for Protease Substrate Mining Using Factor VII Activating Protease (FSAP) as Model

We describe a novel, easy and efficient combinatorial phage display peptide substrate‐mining method to map the substrate specificity of proteases. The peptide library is displayed on the pVII capsid of the M13 bacteriophage, which renders pIII necessary for infectivity and efficient retrieval, in an...

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Detalles Bibliográficos
Autores principales: Kara, Emrah, Nielsen, Nis Valentin, Eggertsdottir, Bergrun, Thiede, Bernd, Kanse, Sandip M., Løset, Geir Åge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383712/
https://www.ncbi.nlm.nih.gov/pubmed/32180321
http://dx.doi.org/10.1002/cbic.201900705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383712/
https://www.ncbi.nlm.nih.gov/pubmed/32180321
http://dx.doi.org/10.1002/cbic.201900705

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