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Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain

LPA(1) is one of six known receptors (LPA(1‐6)) for lysophosphatidic acid (LPA). Constitutive Lpar1 null mutant mice have been instrumental in identifying roles for LPA‐LPA(1) signaling in neurobiological processes, brain development, and behavior, as well as modeling human neurological diseases lik...

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Detalles Bibliográficos
Autores principales: Rivera, Richard R., Lin, Mu‐En, Bornhop, Emily C., Chun, Jerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383719/
https://www.ncbi.nlm.nih.gov/pubmed/32929779
http://dx.doi.org/10.1096/fj.202000317R