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Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats

OBJECTIVE: Approximately 30% of patients with epilepsy do not experience full seizure control on their antiseizure drug (ASD) regimen. Historically, screening for novel ASDs has relied on evaluating efficacy following a single administration of a test compound in either acute electrical or chemical...

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Detalles Bibliográficos
Autores principales: Thomson, Kyle E., Metcalf, Cameron S., Newell, Thomas G., Huff, Jennifer, Edwards, Sharon F., West, Peter J., Wilcox, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383749/
https://www.ncbi.nlm.nih.gov/pubmed/32420627
http://dx.doi.org/10.1111/epi.16531