Pharmacokinetics and safety of VALTOCO (NRL‐1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri‐ictal) and nonseizure (interictal) conditions: A phase 1, open‐label study

OBJECTIVE: To assess pharmacokinetics and safety of diazepam nasal spray (NRL‐1; VALTOCO®) in pediatric and adult patients with epilepsy in seizure and nonseizure states. METHODS: A single dose of diazepam nasal spray (5, 10, 15, or 20 mg based on weight) was administered during each of two conditio...

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Detalles Bibliográficos
Autores principales: Hogan, Robert Edward, Tarquinio, Daniel, Sperling, Michael R., Klein, Pavel, Miller, Ian, Segal, Eric B., Rabinowicz, Adrian L., Carrazana, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383779/
https://www.ncbi.nlm.nih.gov/pubmed/32338380
http://dx.doi.org/10.1111/epi.16506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383779/
https://www.ncbi.nlm.nih.gov/pubmed/32338380
http://dx.doi.org/10.1111/epi.16506

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