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Activation of the RhoA‐YAP‐β‐catenin signaling axis promotes the expansion of inner ear progenitor cells in 3D culture

Cellular mechanotransduction plays an essential role in the development and differentiation of many cell types, but if and how mechanical cues from the extracellular matrix (ECM) influence the fate determination of inner ear progenitor cells (IEPCs) remains largely unknown. In the current study, we...

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Detalles Bibliográficos
Autores principales: Xia, Mingyu, Chen, Yan, He, Yingzi, Li, Huawei, Li, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383802/
https://www.ncbi.nlm.nih.gov/pubmed/32159914
http://dx.doi.org/10.1002/stem.3175