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DNA sequence repeats identify numerous Type I restriction‐modification systems that are potential epigenetic regulators controlling phase‐variable regulons; phasevarions

Over recent years several examples of randomly switching methyltransferases, associated with Type III restriction‐modification (R‐M) systems, have been described in pathogenic bacteria. In every case examined, changes in simple DNA sequence repeats result in variable methyltransferase expression and...

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Detalles Bibliográficos
Autores principales: Atack, John M., Guo, Chengying, Yang, Long, Zhou, Yaoqi, Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383803/
https://www.ncbi.nlm.nih.gov/pubmed/31914596
http://dx.doi.org/10.1096/fj.201901536RR