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DNA sequence repeats identify numerous Type I restriction‐modification systems that are potential epigenetic regulators controlling phase‐variable regulons; phasevarions
Over recent years several examples of randomly switching methyltransferases, associated with Type III restriction‐modification (R‐M) systems, have been described in pathogenic bacteria. In every case examined, changes in simple DNA sequence repeats result in variable methyltransferase expression and...
Autores principales: | Atack, John M., Guo, Chengying, Yang, Long, Zhou, Yaoqi, Jennings, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383803/ https://www.ncbi.nlm.nih.gov/pubmed/31914596 http://dx.doi.org/10.1096/fj.201901536RR |
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