Enantio‐ and Diastereoselective Synthesis of Homopropargyl Amines by Copper‐Catalyzed Coupling of Imines, 1,3‐Enynes, and Diborons

An efficient, enantio‐ and diastereoselective, copper‐catalyzed coupling of imines, 1,3‐enynes, and diborons is reported. The process shows broad substrate scope and delivers complex, chiral homopropargyl amines; useful building blocks on the way to biologically‐relevant compounds. In particular, fu...

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Detalles Bibliográficos
Autores principales: Manna, Srimanta, Dherbassy, Quentin, Perry, Gregory J. P., Procter, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383811/
https://www.ncbi.nlm.nih.gov/pubmed/31917893
http://dx.doi.org/10.1002/anie.201915191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383811/
https://www.ncbi.nlm.nih.gov/pubmed/31917893
http://dx.doi.org/10.1002/anie.201915191

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