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Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model

Epoxyeicosatrienoic acids (EET) and related epoxy fatty acids (EpFA) are endogenous anti‐inflammatory compounds, which are converted by the soluble epoxide hydrolase (sEH) to dihydroxylethersatrienoic acids (DHETs) with lessened biological effects. Inhibition of sEH is used as a strategy to increase...

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Detalles Bibliográficos
Autores principales: Trindade‐da‐Silva, Carlos A., Clemente‐Napimoga, Juliana T., Abdalla, Henrique B., Rosa, Sergio Marcolino, Ueira‐Vieira, Carlos, Morisseau, Christophe, Verri, Waldiceu A., Montalli, Victor Angelo Martins, Hammock, Bruce D., Napimoga, Marcelo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383812/
https://www.ncbi.nlm.nih.gov/pubmed/32400048
http://dx.doi.org/10.1096/fj.202000415R