Cargando…

Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model

Epoxyeicosatrienoic acids (EET) and related epoxy fatty acids (EpFA) are endogenous anti‐inflammatory compounds, which are converted by the soluble epoxide hydrolase (sEH) to dihydroxylethersatrienoic acids (DHETs) with lessened biological effects. Inhibition of sEH is used as a strategy to increase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trindade‐da‐Silva, Carlos A., Clemente‐Napimoga, Juliana T., Abdalla, Henrique B., Rosa, Sergio Marcolino, Ueira‐Vieira, Carlos, Morisseau, Christophe, Verri, Waldiceu A., Montalli, Victor Angelo Martins, Hammock, Bruce D., Napimoga, Marcelo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383812/ https://www.ncbi.nlm.nih.gov/pubmed/32400048 http://dx.doi.org/10.1096/fj.202000415R

Ejemplares similares

Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine
por: Wan, Xiayun, et al.
Publicado: (2020)

The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling
por: Luo, Ailin, et al.
Publicado: (2023)

Secreted Osteoclastogenic Factor of Activated T Cells (SOFAT) Is Associated With Rheumatoid Arthritis and Joint Pain: Initial Evidences of a New Pathway
por: Napimoga, Marcelo Henrique, et al.
Publicado: (2020)

Research progress on the protective mechanism of a novel soluble epoxide hydrolase inhibitor TPPU on ischemic stroke
por: Huang, Pan
Publicado: (2023)

Evaluation of fish models of soluble epoxide hydrolase inhibition.
por: Newman, J W, et al.
Publicado: (2001)

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)

Interleukin-6, tumor necrosis factor-α, C-reactive protein, and hematological parameters in experimental periodontal disease after β-adrenergic blockade
por: Rodrigues, Wellington Francisco, et al.
Publicado: (2019)

Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
por: Wang, Yuxin, et al.
Publicado: (2021)

Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
por: Wagner, Karen M., et al.
Publicado: (2021)

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice
por: Bettaieb, Ahmed, et al.
Publicado: (2014)

Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity
por: Oh, Young Taek, et al.
Publicado: (2023)

Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales
por: Kitamura, Seiya, et al.
Publicado: (2017)

Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis
por: McReynolds, Cindy B., et al.
Publicado: (2019)

Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
por: Imig, John D., et al.
Publicado: (2020)

Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women
por: Nguyen, Nhien, et al.
Publicado: (2022)

Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats
por: Iyer, Abishek, et al.
Publicado: (2012)

Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine
por: Shihadih, Diyala S., et al.
Publicado: (2020)

Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon
por: Wang, Weicang, et al.
Publicado: (2023)

Dysregulation of Soluble Epoxide Hydrolase and Lipidomic Profiles in Anorexia Nervosa
por: Shih, Pei-an Betty, et al.
Publicado: (2015)

Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease
por: Mello, Aline, et al.
Publicado: (2020)

Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues
por: Morisseau, Christophe, et al.
Publicado: (2021)

Aflatoxin B(1) Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity
por: Wang, Weicang, et al.
Publicado: (2023)

Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA
por: Yang, Huiyi, et al.
Publicado: (2023)

Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits
por: Vázquez, Javier, et al.
Publicado: (2023)

Inhibition of the Soluble Epoxide Hydrolase Promotes Albuminuria in Mice with Progressive Renal Disease
por: Jung, Oliver, et al.
Publicado: (2010)

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
por: Martín-López, Juan, et al.
Publicado: (2021)

Development of an online SPE–LC–MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors
por: Schebb, Nils Helge, et al.
Publicado: (2011)

Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain
por: Takeshita, Ashley A., et al.
Publicado: (2023)

Soluble Epoxide Hydrolase Inhibitor TPPU Alleviates Nab-Paclitaxel-Induced Peripheral Neuropathic Pain via Suppressing NF-κB Signalling in the Spinal Cord of a Rat
por: Wei, Xing, et al.
Publicado: (2023)

Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice
por: Qin, Jun, et al.
Publicado: (2015)

Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit
por: McLellan, Gillian J., et al.
Publicado: (2016)

Potent Natural Soluble Epoxide Hydrolase Inhibitors from Pentadiplandra brazzeana Baillon: Synthesis, Quantification, and Measurement of Biological Activities In Vitro and In Vivo
por: Kitamura, Seiya, et al.
Publicado: (2015)

Histological and mast cells evaluation after application of botulinum toxin type a in masseter muscles of rats
por: Blas, Rodrigo, et al.
Publicado: (2022)

Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity
por: Overby, Haley, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase and Diabetes Complications
por: Anita, Natasha Z., et al.
Publicado: (2022)

Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety
por: Burmistrov, Vladimir, et al.
Publicado: (2022)

Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice
por: Yang, Yang, et al.
Publicado: (2021)

Effect of Soluble Epoxide Hydrolase on the Modulation of Coronary Reactive Hyperemia: Role of Oxylipins and PPARγ
por: Hanif, Ahmad, et al.
Publicado: (2016)

Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures
por: Inceoglu, Bora, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8t55pte1jk21vbsj7n2j5btqj9