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A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury

Vascular injury leads to membrane disruption, ATP release, and endothelial dysfunction. Increases in the phosphorylation of p38 mitogen‐activated protein kinase (p38 MAPK) and decreases in the phosphorylation of Niban, a protein implicated in ER stress and apoptosis, are associated with vascular inj...

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Detalles Bibliográficos
Autores principales: Yim, Tsz Wing, Perling, Daniel, Polcz, Monica, Komalavilas, Padmini, Brophy, Colleen, Cheung‐Flynn, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383822/
https://www.ncbi.nlm.nih.gov/pubmed/32396246
http://dx.doi.org/10.1096/fj.201902745R