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A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury
Vascular injury leads to membrane disruption, ATP release, and endothelial dysfunction. Increases in the phosphorylation of p38 mitogen‐activated protein kinase (p38 MAPK) and decreases in the phosphorylation of Niban, a protein implicated in ER stress and apoptosis, are associated with vascular inj...
Autores principales: | Yim, Tsz Wing, Perling, Daniel, Polcz, Monica, Komalavilas, Padmini, Brophy, Colleen, Cheung‐Flynn, Joyce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383822/ https://www.ncbi.nlm.nih.gov/pubmed/32396246 http://dx.doi.org/10.1096/fj.201902745R |
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