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Promoter DNA Methylation Frequency and Clinicopathological Role of miR-129-2 Gene in Patients with Chronic Lymphocytic Leukemia

OBJECTIVES: Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of apparently mature B-type lymphocytes in the lymphohematopoietic organs. Methylation in promoters of tumor suppressor genes is one of the mechanisms that causes blood malignancy. In this study, we evaluated the pro...

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Detalles Bibliográficos
Autores principales: Hashemi, Morteza, Mohammadipour, Mahshid, Rostami, Shahrbano, Soltanpour, Mohammad Soleiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OMJ 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383833/
https://www.ncbi.nlm.nih.gov/pubmed/32724662
http://dx.doi.org/10.5001/omj.2020.71