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Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent

Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening. Although retinal organoids may represent tissue structures with greater physiological relevance to the in vivo human retina, their generation is n...

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Detalles Bibliográficos
Autores principales: Chichagova, Valeria, Hilgen, Gerrit, Ghareeb, Ali, Georgiou, Maria, Carter, Madeleine, Sernagor, Evelyne, Lako, Majlinda, Armstrong, Lyle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383896/
https://www.ncbi.nlm.nih.gov/pubmed/31721366
http://dx.doi.org/10.1002/stem.3116